Abstract: This paper introduces an overall system design study of Unmanned Surface Vehicle (USV) based on MATLAB／BDS. In order to make the USV move more accurately in the autonomous path planning, the USV communicates with the host computer through the wireless communication module to combine the position data information sent by the BeiDou Navigation Satellite System (BDS) with the MATLAB planning path. Through planning and processing of the PC software, the precise motion trajectory is planned,  The control information is sent to the USV, and the entire hull operation is controlled by the embedded control board STM32. The test is based on the real test data, the path planning data with MATLAB, and the path planning data with BDS. Comparing the data with the two-party integrated planning, the results show that the deviation of path planning based on MATLAB／BDS is significantly reduced, providing a feasible method for improving the accuracy of path planning.