Abstract: In the interpolation of satellite clock data, the accuracy of interpolation algorithm directly affects the accuracy of satellite clock interpolation results, which affects the accuracy of satellite navigation and positioning. Therefore, an appropriate interpolation method should be selected when interpolating satellite clock data. In this paper, the Lagrange interpolation method and Chebyshev fitting method are used for sliding, these two traditional interpolation methods and sliding generalized extension interpolation method are used to interpolate the GLONASS clock error data with an epoch interval of 5 min into 30 s. Results are compared with the precision clock error data of 30 s. The application effect of the three interpolation methods in GLONASS satellite clock error data is analyzed. The obtained results show that the interpolation accuracy of these three interpolation methods can meet the requirements of GLONASS satellite clock data interpolation, and the sliding generalized extension interpolation method has the highest interpolation accuracy.